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The
pCLAMP 10 software suite fulfills many different
experimental needs, such as synchronized
stimulation, event detection, and online
analysis. It is the most widely-used data
acquisition and analysis program for the control
and recording of voltage-clamp, current-clamp,
and patch-clamp experiments. Three separate
programs are included: Clampex 10, AxoScope 10,
Clampfit 10.
Clampex
10 expands the range and quality of your data
acquisition experiments. These improvements
should prove useful for a wide variety of
applications, allowing more flexibility in your
experimental protocols.
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Existing
functionality includes the ability to automate
the execution of protocols, a variety of
recording modes from continuous to waveform
stimulation, online filtering and leak
subtraction, and online statistics/graphs.
AxoScope
10 provides a convenient way to produce
background recordings with the included MiniDigi
2-channel digitizer. You can monitor cells
during intra-sweep periods, or create an
overview of the entire day's activities
including voice tags.
Clampfit
10 is a powerful solution for analyzing,
graphing and layout of all of your Clampex and
AxoScope data. Clampfit includes an extensive
array of filtering and fitting routines.
Functionality includes I-V graphs, power
spectrums, and special "linked data
views" for threshold (AP), template (minis)
and single-channel modes of event detection and
analysis.
pCLAMP
10 is suitable for a wide variety of
applications, ranging from electrophysiology to
general physiology, from individual cells to
networked cells, and from low-noise patch
clamping to high-speed sodium channels.
Uses:
Action Potentials (APs) ,Current-clamp,
Electromyography (EMG), Electrooculography
(EOG), Excitatory Post-Synaptic Currents
(EPSCs), Excitatory Post-Synaptic Potentials
(EPSPs), Inhibitory Post-Synaptic Currents
(IPSCs), Inhibitory Post-Synaptic Potentials
(IPSPs), p12 Long-Term Depression (LTD),
Long-Term Potentiation (LTP), Miniature
excitatory potentials (Minis), Ratio
dyes (with PMTs), Single-channels, Slices, Spike
trains, Synaptic networks, Voltage-clamp,
Whole-cell
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